randomization

Simulating A Simple Response Adaptive Randomization - I Have To See It To Believe It

In my simulations of Response Adaptive Randomization, I discovered it performs comparably to fixed 50-50 allocation in identifying treatment effects. The adaptive approach does appear to work! However, with only 10 trials, I’ve merely scratched the surface. Important limitations exist - temporal bias risks, statistical inefficiency, and complex multiplicity adjustments in Bayesian frameworks.